Do you remember the times when "alternative" browsers like #Opera had to masquerade as IE6? That's where we are heading again, thanks to the prevalence of Chromium-based browsers.
Welcome to the dark ages of the web, brought to you by #Microsoft. #Skype web client won't make calls in Chromium on Linux due to some b0rked user agent sniffing (user agent switcher extensions won't help). "Unsupported" Firefox will work just fine however if user agent is changed to Chrome. Feature detection, anyone?
@kaffeeringe brought this up two weeks ago already but I only realized now how thoroughly messed up this is.
On my thread yesterday, @email@example.com and @firstname.lastname@example.org disagreed with my conclusion. In particular, they pointed me to the KeeChallenge plugin which allows #KeePass to use #YubiKey via an offline challenge-response scheme.